Section 11

What Can You Do to Improve the Peak Shape of ...

 

   Bases        Acids

Peak shape, retention and selectivity are the major issues in HPLC separations. Symmetrical peak shapes are desired on every component, because they result in the lowest detection limits and the most accurate quantitation. But there are some compounds that will not chromatograph easily with the most desirable peak shape. Click below for the Column Companion's discussions on what to do to improve the peak shape of different types of compounds.

What Can You Do to Improve the Peak Shape of Bases?

What Can You Do to Improve the Peak Shape of Acids?

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