The HALO Glycan bonded phase has a highly polar ligand that contains five hydroxyl groups tethered to 2.7 µm Fused-Core silica particles via novel, proprietary linkage chemistry. It is particularly useful for hydrophilic interaction liquid chromatography (HILIC) separations for separating released and labeled glycans from glycoproteins and proteoglycans, including monoclonal antibodies.

  • Ideal for HILIC separations of oligosaccharides, especially for enzyme-released and labeled glycans from glycoproteins and proteoglycans
  • Excellent for separating complex mixtures of isobaric oligosaccharides with different linkages
  • Each lot of HALO Glycan packing is tested using a 2-25 glucose unit glycan ladder, and must meet tight specifications for retention and peak width before it can be approved for use
  • Available in 2.7 µm particle size (90 Ångstrom pore size) for UHPLC and HPLC applications

Care and Use Sheets Available on Request (email