Presenter: Alan McKeown, Global Business Development Director, Advanced Chromatography Technologies


In this seminar, we explore the power of stationary phase design to impact selectivity and maximize analyte resolution. Using a variety of chromatographic data, we discuss how incorporating different stationary phases and therefore multiple modes of interaction during method development (that include hydrophobic, π-π, dipole-dipole and shape selectivity) influences the selectivity of reversed-phase separations.

The potent combination of these mechanisms in each unique-C18 based phase provides a new option for the chromatographer with method development platforms or high-throughput screening to influence analyte retention / elution order without compromising separation knowledge. This is further underlined by phase characterization data and also selectivity plots which indicate a high degree of orthogonality when designing stationary phases with multiple modes of interaction.

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