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Technical Notes

Column Conditioning for Protein and Peptide Analysis

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Webinars

Increased Sensitivity and Solvent Savings with Novel 1.5 mm ID Stainless Steel UHPLC Columns

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White Papers

Increasing Sensitivity While Reducing Solvent Consumption with 1.5 mm UHPLC Columns

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Technical Notes

Extracolumn Dispersion’s Impact on Isocratic and Gradient UHPLC Methods

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Technical Notes

Extracolumn Dispersion and How to Reduce it

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Care and Use Sheets

HALO BioClass Protein Diphenyl 400 A Care and Use Sheet

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Catalogs

HALO 1.5 mm Catalog

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Technical Notes

Enhancing Sensitivity of Top-Down and Bottom-Up Proteomic Applications Using a 1.5 mm ID Stainless Steel Column

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White Papers

LC Chromatography Troubleshooting

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Application Guides

Bioapplications Guide

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White Papers

Selecting a Column Geometry and Particle Size for Your Method and Instrument

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LabNotes

White Paper – Analyses of Large Proteins

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Webinars

HPLC Guide to Troubleshooting

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Technical Support

Requesting Technical Support

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Technical Support

Recommended Practices for Starting Off Successfully With a Brand-New Column

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Technical Support

Recommended Practices for Successful Column Flushing and Storage

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Technical Support

Column Cleaning Recommendations

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White Papers

HILIC Analysis for Polar Modifications of Proteins and Peptides

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Webinars

HILIC Analysis for Polar Modifications of mAbs

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Technical Notes

Maintaining LC Column Performance

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Technical Notes

Fat- and Water-Soluble Vitamin Analysis in Supplements

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White Papers

A Novel Approach to Glycan Method Development for Biotherapeutics using Superficially Porous Particle Technology

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Presentations

LC and LC-MS of Intact Protein Biotherapeutics and their Variants and Panel Discussion With Industry Experts

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LabNotes

Factors That Can Affect the Stability, Performance, and Lifetime of Silica-based RPLC Columns

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Webinars

LC and LC-MS of Intact Protein Biotherapeutics and their Variants and Panel Discussion

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Posters

Comparing HILIC and RP for LC-MS Analysis of O-HexNAc Modified Peptides

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Posters

High Efficiency LC-MS Analysis of O-HexNAc Modified Peptides

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Posters

High Efficiency LC-MS Analysis of O-GlcNAc Modified Synthetic Peptides

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Presentations

Optimization of Reversed-Phase HPLC Separations of Biomolecules using HALO® Protein and HALO®-5 Peptide

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Presentations

Optimized Superficially Porous Particles for Peptide and Protein Analysis

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Presentations

Intact Protein and Glycoprotein Separations by HILIC

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Presentations

Bioseparations with 3.4- and 5-Micron Wide-Pore Superficially Porous Particles

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Presentations

Superficially Porous Particles for Peptide and Protein Analysis

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Presentations

Novel wide-pore SPPs for Biomacromolecular Separations

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Presentations

Superficially Porous Silica Particle Technology Developments for Pharma and Biopharma Applications

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Application Guides

HALO® Application Guide

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White Papers

Understanding and Overcoming Separation Challenges in the Biological Drug Development Process

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Care and Use Sheets

HALO® BioClass Protein ES-C18 1000 A Care and Use Sheet

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Care and Use Sheets

HALO® BioClass Protein ES-C18 400 A Nano – Capillary Care and Use Sheet

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Care and Use Sheets

HALO® BioClass Protein ES-C18 400 A Care and Use Sheet

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Care and Use Sheets

HALO® BioClass Protein ES-C18 400 A 1.0 mm Care and Use Sheet

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Care and Use Sheets

HALO® BioClass Protein C4 400 A Nano – Capillary Care and Use Sheet

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Care and Use Sheets

HALO® BioClass Protein C4 400 A Care and Use Sheet

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Care and Use Sheets

HALO® BioClass Protein C4 400 A 1.0 mm Care and Use Sheet

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Care and Use Sheets

HALO® BioClass Peptide Phenyl-Hexyl Nano – Capillary Care and Use Sheet

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Care and Use Sheets

HALO® BioClass Peptide Phenyl-Hexyl 2.7 um Care and Use Sheet

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Care and Use Sheets

HALO® BioClass Peptide ES-CN 5 um Care and Use Sheet

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Care and Use Sheets

HALO® BioClass Peptide ES-CN 2.7 um Care and Use Sheet

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Care and Use Sheets

HALO® BioClass Peptide ES-CN 1.0 mm Care and Use Sheet

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Care and Use Sheets

HALO® BioClass Peptide ES-C18 5 um Care and Use Sheet

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Care and Use Sheets

HALO® BioClass Peptide ES-C18 5 um 1.0 mm Care and Use Sheet

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Care and Use Sheets

HALO® BioClass Peptide ES-C18 2.7 um Care and Use Sheet

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Care and Use Sheets

HALO® BioClass Peptide ES-C18 2.7 um 1.0 mm Care and Use Sheet

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Care and Use Sheets

HALO® BioClass Peptide ES-C18 Nano – Capillary Care and Use Sheet

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Care and Use Sheets

HALO® BioClass Glycan 2.7 um Care and Use Sheet

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Care and Use Sheets

HALO® BioClass Protein Diphenyl 1000 A Care and Use Sheet

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Care and Use Sheets

HALO® BioClass Protein C4 1000 A Care and Use Sheet

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Technical Notes

1000 A Method Development Kit Cards

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Catalogs

HALO® Peptide Phenyl-Hexyl Catalog

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White Papers

Improve Your Analyses of Large Proteins, Antibodies and Antibody-Drug Conjugates Using Reversed-Phase Liquid Chromatography by Maximizing Pore Access

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Catalogs

HALO® Catalog

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Technical Reports

Bioanalysis Solutions Guidebook

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White Papers

Analyses of Large Proteins, Antibodies, and Modified Proteins Using A New Series of Advanced Large Pore HPLC Materials

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Webinars

Understanding and Overcoming Separation Challenges in Biological Drug Development

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Presentations

Protein Separations Using High Performance Large Pore Superficially Porous Particles Optimization Strategies for mAb Variant Resolution

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Posters

High Resolution Separations for Detailed LC-MS Analysis of mAb Disulfide Variants

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Webinars

Protein Separations Using Large Pore Superficially Porous Particles

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Webinars

A Useful Method Development Strategy For Larger Protein Variant RPLC Separations

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Presentations

Optimizing HPLC Separation Performance for Peptides and Other Mid-Size Molecules

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Posters

One Size Does Not Fit All, Exploring the Relationship Between Pore Size and Separation Efficiency

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Posters

A Diphenyl Bonded Phase on Wide Pore Superficially Porous Particles For Efficient Separations of Proteins

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Posters

Selectivity Manipulation for LC-MS Analysis of Protein Variants

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Presentations

Column Pore Size – An Underutilized Variable for Optimizing HPLC Separations

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Webinars

Improving Larger Protein Separations Using 1000 A Superficially Porous Particles

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Posters

Comparison of Phenyl and C18 Bonded Phases with Peptide Mixtures

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Presentations

Size Exclusion Chromatography (SEC) with Superficially Porous (Core-Shell) Particles

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Presentations

Improving Biomolecule Separations with Superficially Porous Particles of Silica

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Posters

Effects of Eliciting Immune Response in Rabbits on IgG N-Glycans

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Posters

Profiling the N-Glycosylation of BioTherapeutic IgGs with HILIC-MRM Analysis of Trypsin Digested Culture Media

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Presentations

Comparison of Phenyl and C18 Bonded Phases to Obtain Separation Selectivity of Peptide Mixtures

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Posters

High Efficiency Wide Pore Superficially Porous Particles for LC-MS of Larger Proteins

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Webinars

Improving the Separation and MS Detection of Proteins and Protein Fragments Using New Mobile Phase Options in Reversed-Phase Chromatography

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Posters

Practical Method Development and Optimization for UHPLC and HPLC Separations of Peptides for Peptide Mapping Analyses Using Different Mobile Phase Additives

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Presentations

Impact of Pore Exclusion on RP-HPLC Column Performance

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Presentations

LC-MS of mAb Structure Utilizing HALO® BioClass Fused-Core® Particles

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Presentations

Improving Superficially Porous Particles for Larger Protein Separations

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Posters

High-Resolution Separations for Protein LC-MS

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Webinars

Unraveling the Structure of a Monoclonal Antibody

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Posters

Improving Protein LC-MS Analysis

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Posters

Utilization of an Isotopically Labelled Glycoprotein Internal Standard to Enable Comparison of Glycan Quantitation

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Posters

LC-MS Analysis of Monoclonal Antibody Structure Utilizing HALO® BioClass Fused-Core® Particles Multilevel Analysis for Proteins and Glycovariants

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Presentations

Advanced Core Shell Particle Technologies Applied to (Bio) Analytical Separations

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Posters

Protein and Glycoprotein LC-MS Using HILIC

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Posters

Novel Superficially Porous HILIC Column Packing Material for High Speed Separations of Biological Molecules

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Presentations

Superficially Porous Silica Particles with Wide Pores for Biomolecular Separations

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Posters

Development of Column Packing Materials and Methods for Proteomics Applications Using LC-MS Detection

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Presentations

Fast, High-Resolution Peptide and Tryptic Digest Separations Using Fused-Core Particles

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Posters

Use of Ammonium Formate to Modify Reversed-Phase LC-MS Analyses of Peptides and Tryptic Digests

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Posters

Rapid High-Resolution Reversed-Phase LC-MS Analyses of Peptides and Tryptic Digests using New Fused-Core Particle Columns

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Posters

Rapid Separations of Polypeptides